Monday, May 16, 2016

Osteogenesis Imperfecta and its Potential Cure


Osteogenesis Imperfecta is a genetic condition that affects roughly 7 in every 100,000 people and results in brittle bones. Osteogenesis Imperfecta is caused by a disruption or change in in chromosome 17 or chromosome 7, causing a failure to produce enough and/or adequate collagen, resulting in brittle bones. There is a recessive form of OI (implying dominant form), as well as 8 types of OI (each type is distinguished with its own symptoms, though there is overlap) where type I is the mildest form and type II is the most severe. OI, while affecting a relatively small portion of the world population, is a horrible hereditary condition, and with the discovery of a treatment for it, we will be able to treat other similar conditions.The change in perspectives is brought on by the use of stem cells to treat OI, as the use of stem cells are somewhat controversial in their own right. That being said, they could also be used in the treatment of countless other genetic conditions.

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